PENGARUH ALKOHOL TERHADAP PENURUNAN BERAT CEREBELLUM PADA TIKUS WISTAR REMAJA

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Suryanti Suryanti

Abstract

Background. Alcohol is a depressant substances that damage the body's
organs. One of the organs that are vulnerable to alcohol consumption , namely
the cerebellum . Consumption of alcohol will damage the cerebellum and lower
density of Purkinje cells thereby reducing the weight of the cerebellum . Alcohol
also mehambat activity of insulin- like growth factor receptor (IGF ) I, which are
growth factors and cell proliferation.
Methods. The purpose of this study was to determine the effect of alcohol on
weight loss cerebellum . This type of research is the study of pure
experimentation with the design of post-test only control group design to
determine the weight of the cerebellum .
Result and Conclusion. Results of this study are in the group of rats that were
given alcohol weight loss than the control group . Analysis cerebellum weight
between groups with multiple comparasion showed that there were significant
differences ( p < 0.05 ) between group B and group A.
Keyword : Cerebellum, Alkohol

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KOSALA : Jurnal Ilmu Kesehatan